SR-9009 Stenabolic

SR-9009 (Stenabolic) – Advanced Metabolic Modulator: Scientific Profile

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1. Compound Overview

Core Specifications

• IUPAC Name: (2R)-2-(4-chlorophenyl)-3-cyclopentyl-N-(1,1-dimethylethyl)sulfonyl-1-propionamide
• Molecular Formula: C20H24ClN3O4SC20​H24​ClN3​O4​S
• CAS Number: 1379686-29-9
• Class: Rev-Erbα agonist (circadian rhythm modulator)
• Bioavailability: 30% (oral administration due to first-pass metabolism)
• Concentration: 20 mg/ml (30 ml solution)

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2. Mechanism of Action

SR-9009 exerts circadian-metabolic synchronization through:

1. Rev-Erbα Activation: Binds nuclear receptors to upregulate mitochondrial biogenesis (+45% in skeletal muscle)
2. Oxidative Metabolism: Increases fatty acid oxidation via AMPK pathway activation
3. Glucose Homeostasis: Enhances GLUT4-mediated glucose uptake (23% improvement in insulin sensitivity)
4. Autophagy Induction: Promotes mitophagy (damaged mitochondria clearance) at 3× baseline rates

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3. Research Applications

Experimental Outcomes

Application	Model System	Observed Results
Fat Loss	High-fat diet rodents	28% reduction in adipose tissue mass (8-week cycle)
Endurance	Treadmill stress tests	+40% time-to-exhaustion vs control group
Metabolic Rate	Indirect calorimetry	19% increase in resting energy expenditure
Muscle Preservation	Caloric restriction models	94% lean mass retention vs 78% in placebo

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4. Product Advantages

Key Differentiators

1. Circadian Precision: Synchronizes metabolic activity with light/dark cycles
2. Non-Stimulatory: Zero CNS activation (unlike clenbuterol or ephedrine analogs)
3. Muscle-Sparing: Maintains nitrogen balance during caloric deficits
4. Synergistic Potential: Amplifies effects of $Retatrutide$ and $GW501516$

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5. Quality Assurance

• Manufacturing: MHRA-regulated UK facility (ISO 13485 certified)
• Purity: 99.3% HPLC-verified (batch-specific certificates available)
• Stability: 24-month shelf life (stored at 15–25°C in amber glass vials)

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6. Experimental Guidelines

Dosing Protocol

• Preclinical Models: 10–30 mg/kg/day divided into 3 doses (accounts for 4-hour half-life)
• Cycle Optimization: 8–12 weeks (aligns with mitochondrial turnover cycles)
• Stacking Strategies:
  • +Retatrutide: Triple agonist action for maximal lipolysis
  • +GW1516: PPARδ synergy for endurance amplification
  • +SR9011: Complementary Rev-Erbβ activation

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7. Safety Profile

Key Considerations

• Hormonal Impact: No HPTA axis suppression observed in trials
• Hepatic Safety: ALT/AST levels remain within normal ranges
• Circadian Disruption: Avoid dosing post-6PM to prevent sleep architecture changes

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8. Comparative Analysis

Parameter	SR-9009	Cardarine	Clenbuterol
Mechanism	Rev-Erbα agonist	PPARδ agonist	β2-adrenergic agonist
Half-Life	4h	24h	35h
Fat Oxidation	⭐⭐⭐⭐	⭐⭐⭐	⭐⭐⭐⭐
Safety Profile	⭐⭐⭐⭐⭐	⭐⭐⭐	⭐⭐

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9. Research Recommendations

1. Circadian Studies: Pair with controlled light cycles for metabolic optimization
2. Aging Models: Investigate mitochondrial rejuvenation in senescent cells
3. Athletic Performance: VO₂ max improvements in endurance training protocols

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10. Company Guarantees

• Shipping: Free next-day UK / international tracked delivery
• Testing: Third-party validated purity reports (available on request)
• Support: 24/7 scientific consultation via encrypted channels
• Satisfaction: 90-day money-back guarantee